Daiichi Sankyo News Monitoring

Merck, Daiichi Sankyo withdraw US appication for patritumab deruxtecan for advanced or metastatic EGFR-mutated non-small ...

Rahway: Daiichi Sankyo and Merck, known as MSD outside of the United States and Canada, have announced that the Biologics License Application (BLA) seeking accelerated approval in the U.S. for patritumab deruxtecan (HER3-DXd), based on the HERTHENA-Lung01 …

Daiichi Sankyo and MSD withdraw US application for lung cancer BLA

Daiichi Sankyo and MSD have voluntarily withdrawn the biologics licence application (BLA) in the US for their HER3-directed DXd antibody drug conjugate (ADC) patritumab deruxtecan, intended for treating non-small cell lung cancer (NSCLC). The withdrawal …

Daiichi Sankyo & Merck voluntarily withdraws patritumab deruxtecan BLA to treat locally advanced or metastatic EGFR-...

The Biologics License Application (BLA) seeking accelerated approval in the US for Daiichi Sankyo and Merck’s, known as MSD outside of the United States and Canada, patritumab deruxtecan (HER3-DXd), based on the HERTHENA-Lung01 phase 2 trial for the …

Merck, Daiichi Sankyo Pull FDA Application For Lung Cancer Therapy: Retail Terms It A ‘Huge Flop’

The decision is based on results from a late-stage trial in which the drug failed to prolong patients' lives, the companies stated. Merck & Co Inc. (MRK) and Daiichi Sankyo on Thursday said that the companies have withdrawn their application to the …

Daiichi Sankyo and Merck Pull Back Patritumab Deruxtecan BLA Based on Phase III HERTHENA-Lung02 Outcomes

Key takeaways BLA withdrawn due to lack of OS benefit: The Phase III HERTHENA-Lung02 trial failed to meet its overall survival endpoint, prompting BLA withdrawal. Regulatory decision unrelated to safety: FDA’s CRL cited manufacturing inspection findings, …

Fortis Open Offer: Daiichi Sankyo's 'misleading' statements continue to damage interests, says NTK

IHH Healthcare's Singapore-headquartered indirect subsidiary Northern TK Venture Pte Ltd (NTK) on Thursday said Daiichi Sankyo's "misleading statements" concerning the Fortis Healthcare open offer continue to damage NTK's interests. …

MSD and Daiichi Sankyo pull HER3-DXd's FDA filing

A year ago, MSD and Daiichi Sankyo's HER3-targeting antibody-drug conjugate patritumab deruxtecan (HER3-DXd) was rejected by the FDA, and the partners have now withdrawn a filing intended to get the programme back on track. The decision to voluntarily …

Merck, Daiichi Sankyo Pull NSCLC Filing for ADC, Citing Underwhelming Survival Findings

Merck and Daiichi Sankyo withdrew their regulatory application Thursday for the investigational antibody-drug conjugate patritumab deruxtecan, which the partners were proposing as a treatment for locally advanced or metastatic non-small cell lung cancer. …

Merck, Daiichi Sankyo pull marketing application for lung cancer therapy

koto_feja/iStock via Getty ImagesMerck (NYSE:MRK) and Daiichi Sankyo (OTCPK:DSNKY) (OTCPK:DSKYF) announced Thursday the voluntary withdrawal of their U.S. marketing application targeted at the FDA’s accelerated approval of the lung cancer therapy …

Merck, Daiichi Sankyo scrap FDA application for HER3 ADC after survival miss

Vepdegestrant may benefit certain patients with advanced breast cancer with ESR1 mutation

Add topic to email alerts Subscribe We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Back to Healio Key takeaways: Vepdegestrant improved PFS for patients with …

ESR1, PIK3CA, and Beyond: Precision Therapy Advances in HR+ Breast Cancer

Hormone receptor-positive (HR+) breast cancer (BC) is the most common subtype of all BC diagnoses, accounting for nearly 70% of all cases. Initial treatment for patients with HR+ BC typically includes CDK4/6 inhibitors, which have led to improved …

At ASCO, Enhertu cements growing role in stomach cancer care

AstraZeneca and Daiichi Sankyo’s targeted cancer medicine Enhertu helped participants in a late-stage clinical trial with a type of advanced gastric cancer live longer than those who received a commonly prescribed, two-drug regimen involving chemotherapy. …

Assay predicts adjuvant chemotherapy benefit in early-stage non-small cell lung cancer

Add topic to email alerts Subscribe We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Back to Healio Key takeaways: A 14-gene molecular assay may help predict …

Second-line trastuzumab deruxtecan improves survival for advanced gastric cancers

Add topic to email alerts Subscribe We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Back to Healio Key takeaways: Second-line trastuzumab deruxtecan-nxki …

ASCO: Gilead bolsters Trodelvy in triple-negative breast cancer with practice-changing Keytruda combo win

Already boasting a strong foothold in metastatic triple-negative breast cancer, Gilead Sciences’ Trodelvy has produced positive data that could make the antibody-drug conjugate part of a new front-line standard of care. In what an American Society of …

STAT+: Combination treatment reduces risk of tumor progression in aggressive form of breast cancer, study shows

CHICAGO — A treatment that combines two different types of cancer-fighting medicines — Gilead Sciences’ Trodelvy with Merck’s Keytruda — reduced the risk of tumor progression by more than one-third in women with an aggressive form of breast cancer.  The …

At ASCO 2025, attendees see reason for hope, despite worries

For more updates on the latest in cancer news, sign up for our Cancer Briefing newsletter here. The annual meeting of the American Society of Clinical Oncology is now in session. As always, STAT has your appetite for cancer news covered. Reporters Matt …

T-DXd Rechallenge Is Safe After Grade 1 ILD in Breast Cancer and Other Solid Tumors

Fam-trastuzumab deruxtecan-nxki (T-DXd; Enhertu) rechallenge was safe and provided a long duration of clinical benefit in patients with breast cancer and other solid tumors who experienced grade 1 interstitial lung disease (ILD) during initial treatment …

San Francisco Dental Implant Center Announces New Content on Convenient Dental Implant Locations in SF

San Francisco Dental Implant Center, a top dental implant center in San Francisco, California, is proud to announce new content focusing on convenient location. SAN FRANCISCO, CA, UNITED STATES, May 31, 2025 /⁨EINPresswire.com⁩/ -- San Francisco …

Libtayo® (cemiplimab) Phase 3 Data in the Adjuvant Treatment of Post-Surgical High-Risk Cutaneous Squamous Cell ...

Libtayo demonstrated a 68% reduction in the risk of disease recurrence or death, the primary endpoint of the trial (p<0.0001) Libtayo also demonstrated 80% and 65% reductions in the risk of locoregional and distant recurrence, respectively, compared to …

Arvinas and Pfizer's Vepdegestrant Significantly Improves Progression-Free Survival for Patients with ESR1-Mutant, ER+/...

Pivotal Phase 3 VERITAC-2 clinical trial results presented at ASCO demonstrate 2.9-month improvement in median progression-free survival when compared to fulvestrant in second line-plus patients with an estrogen receptor 1 mutation Vepdegestrant was …

Nurses for Natural Health Hosts Transformative Yoga Retreat for Nurses in France

PHOENIX , AZ, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- This July, Nurses for Natural Health invites nurses from around the world to join a one-of-a-kind restorative yoga retreat in the picturesque town of Luz-Saint-Sauveur. Designed to …

The Good Feet Store Opens in Seabrook, NH to Help Local Residents and Workforce Live the Life They Love

The Leading Retailer of Premium, Personally-Fitted Arch Supports Expands with the Tenth Store in the Boston Area SEABROOK, NH, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- The Good Feet Store, recognized nationally as the market-leading …

Late-breaking analysis demonstrates characteristics associated with long-term overall survival with Onivyde® regimen in ...

Phase III NAPOLI 3 trial is the largest and has the longest follow-up for an interventional study in metastatic pancreatic adenocarcinoma1 Post-hoc analysis of NAPOLI 3 study determined characteristics associated with long-term survival, with median …

Une analyse « Late Breaking » démontre les caractéristiques associées à la survie globale à long terme des patients avec ...

L’essai de Phase III NAPOLI 3 est la plus grande étude interventionnelle réalisée à ce jour avec la plus longue période de suivi des patients avec un adénocarcinome pancréatique métastatique1. L’analyse post-hoc de l’étude NAPOLI 3 a permis de déterminer …

Harbinger Health Showcases Multi-Cancer Early Detection Performance in High-Risk Populations at ASCO 2025

Reflex blood-based multi-cancer early detection (MCED) test demonstrated clinically meaningful per-cancer Positive Predictive Value (PPV) and early-stage sensitivity for multiple cancers with elevated incidence and mortality in a high-risk population Data …

Xilio Therapeutics Announces Updated Phase 2 Data for Vilastobart, a Tumor-Activated Anti-CTLA-4, in Combination with ...

26% preliminary objective response rate observed in heavily pre-treated patients with metastatic microsatellite stable colorectal cancer (MSS CRC) without liver metastases Deep and durable responses ongoing for up to 37 weeks through the data cutoff, …

From protocol to empathetic accompaniment: improving dialysis care via psychological education

A groundbreaking shift is happening in the treatment of chronic kidney disease thanks to the work of psychologist Mrs. Erika Danitza Rocabado Vargas. RICHMOND, VA, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- With over 19 years of clinical …

NYC Optician French Optical Fashion, Inc. Educates on Eye Wellness

French Optical Fashion, Inc. launches NYC optician campaign to promote eye health with exams and education. NEW YORK, NY, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- French Optical Fashion, Inc., a premier NYC optician located at 7 East …

BREAST CANCER ALLIANCE AWARDS $1.3M IN GRANTS TO ADVANCE RESEARCH, BREAST SURGICAL ONCOLOGY TRAINING, AND ACCESS TO CARE

GREENWICH, CT, CT, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Breast Cancer Alliance (BCA), one of the nation’s leading and most impactful nonprofit breast cancer organizations, proudly announces the awarding of $1.3 million in 2025 grants …

New Book Reveals the Overlooked Toxins Impacting American Homes

A shocking exposé reveals how everyday home materials harm your family—and the proven steps to detox, protect, and rebuild your health. ORLANDO, FL, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- What if the place you trust the most is …

Meaningful Life Counseling Pioneers Early Couples Therapy in CT for Lasting Love

Meaningful Life Counseling in CT promotes early couples therapy to strengthen relationships, offering free consultations to help partners thrive. WOODBRIDGE, CT, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- As couples face mounting …

Mobility City Holdings Inc Celebrates Six Years of Serving People in Lake County Illinois & Surrounding Communities

Kevin Pignone opened his showroom in Grayslake IL with a mission to help people with mobility challenges via the repair, rental and sale of mobility equipment BOCA RATON, FL, US, May 30, 2025 /⁨EINPresswire.com⁩/ -- Mobility City Holdings, Inc., …

Free Training Event During CPR and AED Awareness Week Aims to Equip More People to Act in Emergencies

Hands-on virtual session June 6 empowers participants with the skills and confidence to respond in cardiac emergencies—no experience required. HOUSTON, TX, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- In an effort to empower more …

LosAngelesMedicalMalpracticeLawyers.com Launches to Connect Individuals with Malpractice Lawyers

LOS ANGELES, CA, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- A new website, losangelesmedicalmalpracticelawyers.com, has been launched to assist individuals in the Los Angeles area in finding the best medical malpractice lawyer for their …

A New Initiative for the Wellness of Children and Communities: A Mental Health Awareness Event with U.S. - Japan Experts

～Heartfulness × Hip-Hop Therapy × Expressive Arts Therapy ～“M.O.F.U.” to Be Held for the First Time in Katsushika, Tokyo TOKYO, CA, JAPAN, May 30, 2025 /⁨EINPresswire.com⁩/ -- On Saturday, June 7, 2025, a mental health awareness event titled“M.O.F …

Media Statement By Dr. Gail C. Christopher: America 5 Years After George Floyd’s Murder

Dr. Christopher, leader of the National Collaborative for Health Equity, says racial justice faces headwinds, but accomplishments have not been erased WASHINGTON, DC, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Five years ago, at the …

Cosmetic Dentistry Experts Drs. John and Jade Moreau of Unforgettable Smiles Talk How Enhanced Smiles Build Confidence

ALEXANDRIA, LA, UNITED STATES, May 30, 2025 /⁨EINPresswire.com⁩/ -- Drs. John and Jade Moreau of Unforgettable Smiles is featured in the latest edition of HelloNation, where he shares valuable insight on the role of cosmetic dentistry in improving both …