
Unraveling the role of Ctla-4 in intestinal immune homeostasis through a novel Zebrafish model of inflammatory bowel ...
As an essential negative regulator of T cell activation, dysfunction of CTLA-4 was implicated in various diseases in both humans and murine models (Tivol et al., 1995; Waterhouse et al., 1995; Hosseini et al., 2020). Numerous previous studies have …