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Published on 08:58 GMT

Novartis inks agreement to buy Regulus Therapeutics and farabursen, an investigational microRNA inhibitor to treat ADPKD

Novartis announced that it has entered into an agreement to acquire Regulus Therapeutics, a San Diego-based, publicly traded clinical-stage biopharmaceutical company focused on developing microRNA therapeutics. Regulus’ lead asset, farabursen, is a …

Source: Pharmabiz.com - Neutral
Published on 10:09 GMT

Nephrology Month in Review: April 2025

The nephrology landscape saw meaningful developments in April, from US Food and Drug Administration action on glomerular diseases to studies highlighting ongoing challenges in chronic kidney disease (CKD) and inequities in renal care. In FDA news, the …

Source: Consultant Live - Pending
Published on May 1, 2025

Novartis Gets Phase 3-Ready Rare Kidney Disease Drug via $800M Regulus Acquisition

Novartis has made kidney disorders an area of focus, and it’s now adding a new drug prospect through a deal to acquire Regulus Therapeutics, a biotech with a drug ready for pivotal testing in a rare renal disease that has limited treatment options. The …

Source: MedCity News - Neutral
Published on Apr 30, 2025

Novartis grabs kidney drug developer Regulus in $1.7bn deal

Novartis has reached an agreement to buy Regulus Therapeutics and its experimental therapy for autosomal dominant polycystic kidney disease (ADPKD) for $800 million upfront in a deal that could have a total value of up to $1.7 billion. Shares in the San …

Source: pharmaphorum - Neutral
Published on May 1, 2025

Novartis to acquire Regulus in deal for kidney disease drug

Novartis will pay $800 million upfront to acquire Regulus Therapeutics, a San Diego biotechnology company that launched nearly two decades ago with plans to make drugs capable of targeting small strips of nucleic acid known as microRNA. Announced Wednesday …

Source: BioPharma Dive - Pending
Published on Apr 30, 2025

XORTX Provides Update on FDA Type B Meeting Request

● XORTX will focus on key steps to advance a NDA filing for Gout indication ● CALGARY, Alberta, April 30, 2025 (GLOBE NEWSWIRE) -- XORTX Therapeutics Inc. ("XORTX" or the “Company”) (NASDAQ: XRTX | TSXV: XRTX | Frankfurt: ANU), a late stage …

Distribution channels: Healthcare & Pharmaceuticals Industry, Media, Advertising & PR ...
Published on Apr 30, 2025

Novartis To Buy US Kidney Drug Developer Regulus Therapeutics For Around $800 Million

Novartis AG NVS agreed to acquire Regulus Therapeutics Inc. RGLS on Wednesday for an initial payment of $7.00 per share in cash or $0.8 billion. The upfront cash portion of the consideration represents a premium of 274% to Regulus’ 60-day volume-weighted …

Source: Benzinga - Neutral
Published on Apr 30, 2025

TEX10: A Novel Drug Target and Potential Therapeutic Direction for Sleep Apnea Syndrome

Introduction Sleep apnea syndrome (SAS) is characterized by recurrent episodes of complete (apnea) or partial (hypopnea) upper airway obstruction during sleep, with each episode lasting ≥10 seconds and occurring ≥5 times per hour of sleep.1,2 Based on …

Source: Dove Medical Press - Neutral
Published on Apr 30, 2025

Novartis To Acquire Regulus Therapeutics And Farabursen, An Investigational Microrna Inhibitor To Treat ADPKD, The Most ...

(MENAFN- GlobeNewsWire - Nasdaq) Regulus is a clinical-stage biopharmaceutical company developing microRNA therapeutics with a focus on autosomal dominant polycystic kidney disease (ADPKD), a severe renal disease Lead asset for ADPKD, farabursen, is a …

Source: MENAFN - Indeterminate
Published on Apr 29, 2025

The Evolving IgAN Treatment Landscape and Advances in FSGS, with Sayna Norouzi, MD

For many years, patients with IgA nephropathy (IgAN) and focal segmental glomerulosclerosis (FSGS) and their nephrologists have faced a frustrating reality: the absence of FDA-approved therapies. Instead, treatment largely relied on supportive measures, …

Source: Consultant Live - Pending
Published on Apr 29, 2025

EMA grants orphan drug designation to Purespring Therapeutics' PS─002 to treat patients with primary IgA nephropathy

Purespring Therapeutics, a pioneering company focused on transforming the treatment of kidney diseases, announces that the European Medicines Agency (EMA) has granted orphan drug designation to PS-002, Purespring’s lead programme, in IgA nephropathy (IgAN …

Source: Pharmabiz.com - Neutral
Published on Apr 29, 2025

EMA grants orphan drug status to Purespring’s IgA nephropathy treatment

The European Medicines Agency (EMA) has granted orphan drug designation to UK-based Purespring Therapeutics’ lead candidate, PS-002, aimed at treating IgA nephropathy (IgAN). This status is conferred by the European Commission following a positive opinion …

Source: Pharmaceutical Business Review - Pending
Published on Apr 29, 2025

CSL Vifor and Travere Therapeutics announce standard EU approval for FILSPARI® in IgA Nephropathy

European Commission converts conditional approval of FILSPARI (sparsentan) into standard marketing authorization for the treatment of IgA Nephropathy (IgAN) Decision follows positive recommendation from Committee for Medicinal Products for Human Use (CHMP) …

Source: WFMZ - Pennsylvania - Neutral
Published on May 1, 2025

Protective Role of H2S in High Glucose-Induced Cardiomyocyte and Endothelial Cell Dysfunction: A Mechanistic Review

Introduction Hydrogen sulfide (H2S) is a colorless gas characterized by its toxicity, corrosiveness, and flammability, and is prevalent in both environmental and industrial pollutants.1,2 Recent research has demonstrated that H2S is integral to cellular …

Source: Dove Medical Press - Neutral
Published on Apr 30, 2025

FABHALTA Set to Disrupt Complement Inhibitor Market with Oral Convenience and Strong Efficacy | DelveInsight

With future approvals of FABHALTA, the market size is expected to expand significantly in the coming years, driven by its potential to address unmet medical needs across multiple conditions like IgAN, PNH, and other complement-driven diseases. LAS VEGAS, …

Source: WFMZ - Pennsylvania - Neutral
Published on Jan 2, 2025

Regulatory tracker: AbbVie's Rinvoq scores 9th FDA nod, this time in GCA

Welcome to Fierce Pharma's regulatory tracker for the first half of 2025. On this page, we're recording the regulatory progress of in-market products, including expansions into key geographies and new indications. Be sure to come back regularly for …

Source: Fierce Pharma - Neutral
Published on Feb 23, 2024

Human medicines European public assessment report (EPAR): Filspari, Sparsentan, Date of authorisation: 19/04/2024, ...

Filspari has been found to be effective at reducing proteinuria in people with immunoglobulin A nephropathy in a main study. The study involved 404 adults with immunoglobulin A nephropathy and high levels of proteinuria (at least 1 g per day) despite …

Source: European Medicines Agency - Pending
Published on Apr 30, 2025

Dimerix and Amicus Therapeutics Announce Exclusive License Agreement for DMX-200 in the United States

Amicus licenses exclusive U.S. rights to commercialize DMX-200 for the treatment of Focal Segmental Glomerulosclerosis (FSGS) DMX-200 is in a pivotal Phase 3 trial for FSGS, a rare and fatal kidney disease with no FDA-approved therapies Dimerix …

Distribution channels: Companies, Technology ...
Published on Apr 30, 2025

Jade Biosciences Completes Closing of Merger with Aerovate Therapeutics and $300 Million Private Placement Financing

Jade Biosciences Completes Closing of Merger with Aerovate Therapeutics and $300 Million Private Placement Financing Company is advancing portfolio of novel therapies that aim to redefine the standard of care for patients with autoimmune diseases Lead …

Source: T-Net - Pending

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Published on May 2, 2025 - 15:48 GMT

Adial Pharmaceuticals Announces a Warrant Inducement Transaction for $2.75 Million in Gross Proceeds

GLEN ALLEN, Va., May 02, 2025 (GLOBE NEWSWIRE) -- Adial Pharmaceuticals, Inc. (NASDAQ: ADIL) (“Adial” or the “Company”), a clinical-stage biopharmaceutical company focused on developing therapies for the treatment and prevention of addiction and related …

Distribution channels: Banking, Finance & Investment Industry, Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 10:52 GMT

Omega-3 Market Poised for Robust Growth with Expanding Applications Across Nutrition, Pharmaceuticals & Personal Care

Omega 3 Market Research Report By Source, By Form, By Application, By End Use and By Regional-Forecast to 2035 NEW YORK, NY, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- The global Omega-3 Market is experiencing significant momentum, driven …

Distribution channels: Food & Beverage Industry ...

Published on May 2, 2025 - 14:54 GMT

Zinc Chloride Market Poised for 5.0% CAGR Growth: Increasing Demand in Batteries, Water Treatment, and Pharmaceuticals

The global zinc chloride market is set to grow from USD 341.3 million in 2025 to USD 556.0 million by 2035, expanding at a CAGR of 5.0%. NEWARK, DE, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- The global zinc chloride market is projected to …

Distribution channels: Chemical Industry ...
Published on May 2, 2025 - 17:48 GMT

Class Action Filed Against Actinium Pharmaceuticals, Inc. (ATNM) Seeking Recovery for Investors – Contact Levi & ...

NEW YORK, May 02, 2025 (GLOBE NEWSWIRE) -- Levi & Korsinsky, LLP notifies investors in Actinium Pharmaceuticals, Inc. ("Actinium" or the "Company") (NYSE: ATNM) of a class action securities lawsuit. CLASS DEFINITION: The lawsuit …

Distribution channels: Consumer Goods, Law ...

Published on May 2, 2025 - 12:00 GMT

ARS Pharmaceuticals Announces Co-Promotion Agreement with Partner and Global Allergy Leader ALK-Abelló A/S to Expand ...

Agreement builds on landmark licensing deal between ARS Pharma and ALK-Abelló A/S, which provided ARS Pharma with $145 million upfront and ALK with commercialization rights to neffy in Canada, United Kingdom, European Union and certain other countries …

Distribution channels: Companies, Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 10:03 GMT

Rosuvastatin Calcium Market CAGR 5.11 % with Growth USD 940.6 Billion by 2033

Rosuvastatin Calcium market size in 2025 is estimated to be 631.33 million, with projections to grow to 940.6 million by 2033 at a CAGR of 5.11%. PUNE, MAHARASHTRA, INDIA, May 2, 2025 /⁨EINPresswire.com⁩/ -- "Rosuvastatin Calcium Market" …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 06:30 GMT

Nxera Pharma Operational Highlights and Consolidated Results for the First Quarter 2025

Tokyo, Japan and Cambridge, UK, 2 May 2025 – Nxera Pharma (“the Company” or “Nxera”; TSE: 4565) provides an update on operational activities and reports its consolidated results for the first quarter ended 31 March 2025. The full report can be found here. …

Distribution channels: Healthcare & Pharmaceuticals Industry, Media, Advertising & PR ...
Published on May 2, 2025 - 14:11 GMT

NBCI Honors Dr. James H. Powell and Past and Present Black Clinicians Who Have Promoted Diversity in Clinical Trials

Passing the Baton to the National Clinical Trials Strategies Plan (NCTSP) WASHINGTON, DC, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- The National Black Church Initiative (NBCI), a coalition of 150,000 African American churches and 27.7 …

Distribution channels: Education, Healthcare & Pharmaceuticals Industry ...

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Published on May 2, 2025 - 19:38 GMT

The Springs of Ballentine to Open New Memory Care Community in Fuquay-Varina, NC

A new chapter in compassionate care is set to begin as The Springs of Ballentine, a thoughtfully designed memory care community, opens its doors on May 8, 2025 FUQUAY-VARINA, NC, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- The Springs of Ballentine …

Distribution channels: Building & Construction Industry, Companies ...
Published on May 2, 2025 - 19:22 GMT

Global IT Signs Managed Services Agreement with Alzheimer’s Los Angeles

Partnership Aims to Enhance Operational Efficiency and Support Mission-Driven Technology Solutions for Alzheimer’s Los Angeles LOS ANGELES, CA, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- Global IT, a top-tier provider of Managed IT …

Distribution channels: Emergency Services, Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 19:14 GMT

Groundbreaking Ceremony for School-Based Health Center in Piketon, Ohio

New Facility To Serve Students, Community PIKETON, OH, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- The Scioto Valley Local School District, alongside Valley View Health Centers, recently held a groundbreaking ceremony for a transformative $ …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 19:00 GMT

AST Announces the Return of the IP3 for 2025 – A Unique Patent Purchase and Licensing Opportunity for Patent Owners

AST announces its tenth annual Industry Patent Purchase and Licensing Program - IP3 2025, connecting patent owners with major global technology firms. PRINCETON, NJ, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- Allied Security Trust (AST) is …

Distribution channels: Automotive Industry, Banking, Finance & Investment Industry ...
Published on May 2, 2025 - 18:38 GMT

Capy Launches Ponytail Cap: A Stylish & Secure Solution for Healthcare Professionals with Longer Hair

Seattle's Capy launches Ponytail Cap, a comfortable & stylish solution for healthcare pros with voluminous hair. SEATTLE, WA, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- Capy (yourcapy.com), the beloved direct-to-consumer brand known for …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 18:13 GMT

Pennsylvania Dental Association Installs Dr. Theodore Rockwell as President

HARRISBURG, PA, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- The Pennsylvania Dental Association (PDA) recently installed Dr. Theodore J. Rockwell of Clarion as its 2025-2026 president, during its annual business meeting on April 26 at The …

Distribution channels: Healthcare & Pharmaceuticals Industry, International Organizations ...
Published on May 2, 2025 - 18:08 GMT

ACHS Leadership Shares Insights on Innovation, Institutional Storytelling, and AI at WASC ARC 2025

ACHS leaders shared strategies on AI, innovation, and storytelling in higher ed at WASC ARC 2025, highlighting their commitment to academic excellence. PORTLAND, OR, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- American College of Healthcare …

Distribution channels: Business & Economy, Conferences & Trade Fairs ...
Published on May 2, 2025 - 18:02 GMT

Mexico Bariatric Center® Introduces Innovative SASI-S Procedure: Get Sassy with SASI

Mexico Bariatric Center now offers the advanced Single Anastomosis Sleeve Ileal (SASI) bypass for powerful, lasting weight loss and improved metabolic health. SACRAMENTO, CA, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- Mexico Bariatric …

Distribution channels: Beauty & Hair Care, Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 17:57 GMT

Fremont Pediatric Dental: Celebrating 50+ Years of 5-Star Pediatric Dentistry in Fremont, CA

FREMONT, CA, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- For more than 50 years, Fremont Pediatric Dental has been a pillar of excellence in children’s oral health across Bay Area. Today, Fremont Pediatric Dentistry proudly continues to …

Distribution channels: Culture, Society & Lifestyle, Emergency Services ...
Published on May 2, 2025 - 17:37 GMT

American Behavioral Clinics Launches SPRAVATO® Treatment for Depression at Oak Creek Location

American Behavioral Clinics (ABC) is proud to announce the launch of SPRAVATO® (esketamine) treatment at its Oak Creek clinic. OAK CREEK, WI, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- American Behavioral Clinics (ABC), a trusted provider …

Distribution channels: Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 17:35 GMT

World Fellowship Ride Charity Promotes the Franki Moscato Foundation

American Idol Winner's Suicide Prevention Cause Chosen by World Motorcycle Movement OSHKOSH, WI, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- In its second year in the United States, the (May 10th) Fellowship Ride will gift all its event …

Distribution channels: Business & Economy, Culture, Society & Lifestyle ...
Published on May 2, 2025 - 17:30 GMT

PINYA XP f/k/a Pineapple Express Cannabis Company, Announces Engagement of Independent Auditor for Fiscal Year 2025

"PINYA XP engages Aloba, Awomolo & Partners to audit FY 2025 financials, reinforcing commitment to transparency and governance" Pineapple Express Cannabis Company (OTCMKTS:PNXP) ATLANTA, GA, UNITED STATES, May 2, 2025 /⁨EINPresswire.com …

Distribution channels: Agriculture, Farming & Forestry Industry, Banking, Finance & Investment Industry ...
Published on May 2, 2025 - 17:09 GMT

Understanding How ADD Manifests Across Childhood, Adolescence, and Adulthood

GULFPORT, MS, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- Attention Deficit Disorder (ADD), a neurodevelopmental condition affecting focus, organization, and impulse control, manifests differently across various stages of life. Recognizing …

Distribution channels: Culture, Society & Lifestyle, Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 17:00 GMT

EIN Presswire’s Debut Edition of ‘Heard on the Streets': PR Expert Clears Up Important PR Misconception

Sherrie Handrinos discusses how to earn media coverage and the key differences between earned PR and paid placement WASHINGTON, DC, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- In the debut edition of “Heard on the Streets,” a new series on …

Distribution channels: Agriculture, Farming & Forestry Industry, Amusement, Gaming & Casino ...
Published on May 2, 2025 - 16:42 GMT

Ascend, Inc. Celebrates a Decade of Great With Great Place To Work®

Ascend Joins Special Event Honoring 10+ Years of Great Place To Work Certification in 2025 BOULDER, CO, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- Ascend, Inc., a Great Place To Work® Certified™ workplace, recently received a special …

Distribution channels: Building & Construction Industry, Companies ...
Published on May 2, 2025 - 16:33 GMT

USGrants.org Tracks Over $683 Million in Federal Funding for Higher Education Programs

USGrants.org Tracks Over $683 Million in Federal Funding for Higher Education Programs SACRAMENTO, CA, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- USGrants.org, an online resource for federal grant information in the United States, has …

Distribution channels: Agriculture, Farming & Forestry Industry, Banking, Finance & Investment Industry ...
Published on May 2, 2025 - 16:08 GMT

Etech's QEval Wins the Spring 2025 Top Performer Award from SourceForge

Etech's QEval is proud to be a winner of the Top Performer award from SourceForge, the world's largest software reviews and comparison website. NACOGDOCHES, TX, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- Etech Global Services, a …

Distribution channels: Banking, Finance & Investment Industry, Business & Economy ...
Published on May 2, 2025 - 15:41 GMT

Hypnosis Business Virtual Summit to Take Place June 21-22, 2025, Sponsored by HypnoBiz-in-a-Box™

The Hypnosis Business Virtual Summit is a 2-day event with expert insights for hypnosis business owners, featuring presentations from top industry leaders. TAMPA, FL, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- The Hypnosis Education …

Distribution channels: Business & Economy, Conferences & Trade Fairs ...
Published on May 2, 2025 - 15:00 GMT

The Brookbush Institute Publishes NEW Course and Glossary Updates: 'Taut Band'

The Brookbush Institute continues to enhance education with new courses, a modern glossary, an AI Tutor, and a client program generator. NEW YORK, NY, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- Excerpt from the glossary term: Taut Band …

Distribution channels: Education, Healthcare & Pharmaceuticals Industry ...
Published on May 2, 2025 - 14:43 GMT

Iylon Precision Oncology, LLC Introduces Its Visionary Executive Team Revolutionizing Cancer Care

Meet the Iylon Precision Oncology, LLC Executive Team, who are passionate about making a positive difference in cancer patients' lives. PROVIDENCE, RI, UNITED STATES, May 2, 2025 /⁨EINPresswire.com⁩/ -- Precision oncology is more effective …

Distribution channels: Education, Healthcare & Pharmaceuticals Industry ...